Inova Names Milton L. Brown, MD, PhD, Director of the New Inova Center for Drug Discovery and Development and Targeted Therapeutics
Milton L. Brown, MD, PhD, has recently joined Inova. He will serve as director of the new Inova Center for Drug Discovery and Development and as deputy director for Drug Discovery for the Inova Schar Cancer Institute (ISCI). Dr. Brown is a physician scientist who has...
Targeted Nanoparticle Delivery of Paclitaxel
Virginia Tech scientists have developed a cancer drug that increases the effectiveness of a common chemotherapy treatment and dramatically reduces devastating side effects, such as hair loss, nausea, and nerve pain. The new drug uses gold nanoparticles created by the...
Santos & Lynch developing SphK inhibitors
A drug discovery team headed by Webster Santos, Associate professor of Chemistry and member of the Virginia Tech Center for Drug Discovery, and Kevin Lynch, Professor of Pharmacology at the University of Virginia, School of Medicine, is developing inhibitors of...
Potential drug therapy for radiation exposure
Potential new treatments for radiation exposure: The investigators exploited an optimized, cell-based,high throughput screening assay to interrogate a small molecule library comprising 3437 known pharmacologically active compounds for mitigation against IR-induced...
Drug discovery researchers identify, refine compound to combat malaria parasite
The need for new antimalarial drugs is dire, and this work identifies attractive lead compounds for drug development as well as important probes for dissecting a key antimalarial drug target, the non-mevalonate pathway for isoprenoid biosynthesis. This pathway does...